The Veterinary Medicines Directorate (VMD) is an Executive Agency of the Department for Environment, Food and Rural Affairs (Defra) and is responsible for ensuring the safety, quality and efficacy of veterinary medicines in the UK within the statutory framework of various EC Directives and Regulations, and the Veterinary Medicines Regulations.The Veterinary Medicines Directorate (VMD) is an Executive Agency of the Department for Environment, Food and Rural Affairs (Defra) and is responsible for ensuring the safety, quality and efficacy of veterinary medicines in the UK within the statutory framework of various EC Directives and Regulations, and the Veterinary Medicines Regulations.